INVITRO ACTIVITY OF RO-23-9424 AGAINST CLINICAL ISOLATES OF LEGIONELLA SPECIES

被引：14

作者：

EDELSTEIN, PH ^{[1
]}

EDELSTEIN, MAC ^{[1
]}

机构：

[1] UNIV PENN,SCH MED,DEPT MED,PHILADELPHIA,PA 19104

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1992年 / 36卷 / 11期

关键词：

D O I：

10.1128/AAC.36.11.2559

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Agar and broth microdilution MICs of Ro 23-9424 that inhibited 90% of 22 Legionella clinical isolates tested were 0.64 and 0.08 mug/ml, respectively; respective erythromycin values were 1.0 and 0.12 mug/ml. Ro 23-9424 (1 mug/ml) was slightly more active than the same erythromycin concentration in a macrophage system, for both Legionella pneumophila strains studied.

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页码：2559 / 2561

页数：3

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