T-CELL CO-RECEPTORS - THE END OF A FRUSTRATING SEARCH

被引：5

作者：

BENOIST, C ^{[1
]}

MATHIS, D ^{[1
]}

机构：

[1] INST CHIM BIOL,INSERM,UNITE BIOL MOLEC 184,F-67085 STRASBOURG,FRANCE

来源：

CURRENT BIOLOGY | 1994年 / 4卷 / 09期

关键词：

D O I：

10.1016/S0960-9822(00)00182-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The identification of a 'silencer' element that turns off CD4 gene expression at specific stages in thymocyte differentiation may help to resolve an important outstanding problem in immunology.

引用

页码：821 / 823

页数：3

共 13 条

[1] RECONSTITUTION OF THE SUBCLASS-SPECIFIC EXPRESSION OF CD4 IN THYMOCYTES AND PERIPHERAL T-CELLS OF TRANSGENIC MICE - IDENTIFICATION OF A HUMAN CD4 ENHANCER
BLUM, MD
WONG, GT
HIGGINS, KM
SUNSHINE, MJ
LACY, E
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (05) : 1343 - 1358
[2] TOWARDS AN INTEGRATED VIEW OF THYMOPOIESIS
BOYD, RL
HUGO, P
[J]. IMMUNOLOGY TODAY, 1991, 12 (02): : 71 - +
[3] CHARACTERIZATION OF A SILENCER IN YEAST - A DNA-SEQUENCE WITH PROPERTIES OPPOSITE TO THOSE OF A TRANSCRIPTIONAL ENHANCER
BRAND, AH
BREEDEN, L
ABRAHAM, J
STERNGLANZ, R
NASMYTH, K
[J]. CELL, 1985, 41 (01) : 41 - 48
[4] A CHALLENGE TO THE INSTRUCTIVE MODEL OF POSITIVE SELECTION
CHAN, SH
BENOIST, C
MATHIS, D
[J]. IMMUNOLOGICAL REVIEWS, 1993, 135 : 119 - 131
[5] TISSUE-SPECIFIC EXPRESSION OF HUMAN CD4 IN TRANSGENIC MICE
GILLESPIE, FP
DOROS, L
VITALE, J
BLACKWELL, C
GOSSELIN, J
SNYDER, BW
WADSWORTH, SC
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (05) : 2952 - 2958
[6] SPECIFIC EXPRESSION OF THE HUMAN CD4 GENE IN MATURE CD4+ CD8- AND IMMATURE CD4+ CD8+ T-CELLS AND IN MACROPHAGES OF TRANSGENIC MICE
HANNA, Z
SIMARD, C
LAPERRIERE, A
JOLICOEUR, P
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (02) : 1084 - 1094
[7] REGULATED EXPRESSION OF HUMAN CD4 RESCUES HELPER T-CELL DEVELOPMENT IN MICE LACKING EXPRESSION OF ENDOGENOUS CD4
KILLEEN, N
SAWADA, S
LITTMAN, DR
[J]. EMBO JOURNAL, 1993, 12 (04) : 1547 - 1553
[8] CHARACTERIZATION OF THE HUMAN CD4 GENE PROMOTER - TRANSCRIPTION FROM THE CD4 GENE CORE PROMOTER IS TISSUE-SPECIFIC AND IS ACTIVATED BY ETS PROTEINS
SALMON, P
GIOVANE, A
WASYLYK, B
KLATZMANN, D
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (16) : 7739 - 7743
[9] T-CELL-SPECIFIC PROTEIN-DNA INTERACTIONS OCCURRING AT THE CD4 LOCUS - IDENTIFICATION OF POSSIBLE TRANSCRIPTIONAL CONTROL ELEMENTS OF THE MURINE CD4 GENE
SANDS, JF
NIKOLICZUGIC, J
[J]. INTERNATIONAL IMMUNOLOGY, 1992, 4 (10) : 1183 - 1194
[10] IDENTIFICATION AND CHARACTERIZATION OF A T-CELL-SPECIFIC ENHANCER ADJACENT TO THE MURINE CD4 GENE
SAWADA, S
LITTMAN, DR
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (11) : 5506 - 5515

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