IDENTIFICATION OF A MEMBER OF MOUSE SEMAPHORIN FAMILY

被引：59

作者：

INAGAKI, S

FURUYAMA, T

IWAHASHI, Y

机构：

[1] OSAKA UNIV,FAC MED,DEPT ANAT 2,SUITA 565,OSAKA,JAPAN

[2] OSAKA UNIV,FAC MED,DEPT OPHTHALMOL,SUITA 565,OSAKA,JAPAN

来源：

FEBS LETTERS | 1995年 / 370卷 / 03期

关键词：

SEMAPHORIN; COLLAPSIN; AXON GUIDANCE; CLONING; TRANSMEMBRANE; MOUSE;

D O I：

10.1016/0014-5793(95)00850-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Grasshopper semaphorin I (Sema I) and its related proteins, thick collapsin and mouse Sema III contribute to the axon guidance by their repellent actions [5,9,12], We have identified a member of semaphorin gene family from the mouse brain and named it M-Sema F, The N-terminal encodes a semaphorin domain that is similar between Sema I-III [6] followed by a single putative immunoglobulin-like domain, a transmembrane domain, and a proline-rich intracellular domain, M-Sema F mRNA is expressed widely in the nervous tissues during development, These suggest that M-Sema F is a transmembrane member of the semaphorin family of the vertebrate which may function in the developing neuronal network.

引用

页码：269 / 272

页数：4

共 15 条

[1] CHOMCZYNSKI P, 1987, ANAL BIOCHEM, V162, P156, DOI 10.1016/0003-2697(87)90021-2
[2] AXON GUIDANCE - A COMPELLING CASE FOR REPELLING GROWTH
DODD, J
SCHUCHARDT, A
[J]. CELL, 1995, 81 (04) : 471 - 474
[3] LOCALIZATIONS OF ALPHA-1-SUBUNIT AND BETA-1-SUBUNIT OF SOLUBLE GUANYLATE-CYCLASE IN THE RAT-BRAIN
FURUYAMA, T
INAGAKI, S
TAKAGI, H
[J]. MOLECULAR BRAIN RESEARCH, 1993, 20 (04): : 335 - 344
[4] Kennedy Timothy E., 1995, Current Opinion in Neurobiology, V5, P83, DOI 10.1016/0959-4388(95)80091-3
[5] FASCICLIN-IV - SEQUENCE, EXPRESSION, AND FUNCTION DURING GROWTH CONE GUIDANCE IN THE GRASSHOPPER EMBRYO
KOLODKIN, AL
MATTHES, DJ
OCONNOR, TP
PATEL, NH
ADMON, A
BENTLEY, D
GOODMAN, CS
[J]. NEURON, 1992, 9 (05) : 831 - 845
[6] THE SEMAPHORIN GENES ENCODE A FAMILY OF TRANSMEMBRANE AND SECRETED GROWTH CONE GUIDANCE MOLECULES
KOLODKIN, AL
MATTHES, DJ
GOODMAN, CS
[J]. CELL, 1993, 75 (07) : 1389 - 1399
[7] THE SCANNING MODEL FOR TRANSLATION - AN UPDATE
KOZAK, M
[J]. JOURNAL OF CELL BIOLOGY, 1989, 108 (02) : 229 - 241
[8] A SIMPLE METHOD FOR DISPLAYING THE HYDROPATHIC CHARACTER OF A PROTEIN
KYTE, J
DOOLITTLE, RF
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1982, 157 (01) : 105 - 132
[9] COLLAPSIN - A PROTEIN IN BRAIN THAT INDUCES THE COLLAPSE AND PARALYSIS OF NEURONAL GROWTH CONES
LUO, YL
RAIBLE, D
RAPER, JA
[J]. CELL, 1993, 75 (02) : 217 - 227
[10] Luo Yuling, 1994, Current Opinion in Neurobiology, V4, P648, DOI 10.1016/0959-4388(94)90005-1

← 1 2 →