RESPONSE OF AMOEBAE TO NEOMYCIN AND KANAMYCIN - EVIDENCE OF AN ADDITIONAL CYTOPLASMICALLY-INHERITED CHARACTER

被引：10

作者：

HAWKINS, SE

WILLIS, LR

机构：

[1] Department of Zoology, King's College, London

来源：

EXPERIMENTAL CELL RESEARCH | 1969年 / 54卷 / 02期

关键词：

D O I：

10.1016/0014-4827(69)90251-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The response of two strains of amoebae, A. proteus and A. discoides, to varying concentrations of neomycin and kanamycin has been investigated. The two strains showed no difference in their response to kanamycin. Between 0.4-1.0 μg/ml of neomycin, A. proteus was more sensitive than A. discoides. The heterotransfers between these strains showed that both nucleus and cytoplasm areable to confer lowered sensitivity to neomycin. Examination of clones derived from microinjection of A. discoides cytoplasm into A. proteus showed that lowered sensitivity to neomycin could be transferred. © 1969.

引用

页码：275 / +

页数：1

共 9 条

[1]

BROCK T. D., 1966, SYMP SOC GEN MICROBIOL, V16, P131

[2] NUCLEAR-CYTOPLASMIC INTERACTIONS IN RESPONSES OF AMOEBA PROTEUS AND AMOEBA DISCOIDES TO STREPTOMYCIN [J].