RELATIONSHIP BETWEEN ORAL CONTRACEPTIVE AND FOLIC ACID METABOLISM - SERUM FOLATE CONCENTRATIONS

被引:41
作者
MCLEAN, FW
HEINE, MW
HELD, B
STREIFF, RR
机构
[1] Department of Obstetrics and Gynecology, College of Medicine, University of Florida, Gainesville, FL
[2] Department of Medicine, College of Medicine, University of Florida, Gainesville, FL
关键词
D O I
10.1016/0002-9378(69)90619-X
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
A study of women who developed severe megaloblastic anemia while receiving oral contraceptive agents prompted a hematologic investigation of individuals taking such drugs. A group of patients receiving two different oral contraceptives has been evaluated and compared to a control series. No subjects became folate deficient. There does not appear to be any significant relationship between the duration of therapy and the serum folate level. The exact interaction between folic acid and estrogen remains to be determined. © 1969.
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页码:745 / &
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