INDUCTION BY PARATHYROID-HORMONE OF ORNITHINE DECARBOXYLASE IN RABBIT COSTAL CHONDROCYTES IN CULTURE

被引：32

作者：

TAKIGAWA, M ^{[1
]}

WATANABE, R ^{[1
]}

ISHIDA, H ^{[1
]}

ASADA, A ^{[1
]}

SUZUKI, F ^{[1
]}

机构：

[1] OSAKA UNIV,FAC DENT,DEPT BIOCHEM & CALCIFIED TISSUE METAB,OSAKA 530,JAPAN

来源：

JOURNAL OF BIOCHEMISTRY | 1979年 / 85卷 / 01期

关键词：

D O I：

10.1093/oxfordjournals.jbchem.a132326

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The activity of ornithine decarboxylase (ODC) in rabbit costal chondrocytes in culture markedly increased after addition of parathyroid hormone (PTH), reaching a maximum 4 to 5 h after PTH addition. The effect of PTH was dose-dependent both in the presence and absence of fetal calf serum. Addition of cycloheximide or actinomycin D prevented the induction of ODC by PTH. Calcitonin, 1,25-dihydroxyvitamin D3 and vitamin A had no stimulatory effect on the activity of ODC, and did not inhibit the induction of ODC by PTH, when added with PTH. © 1979 By The Journal Of Biochemistry.

引用

页码：311 / 314

页数：4

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