PHOTO-CHEMICAL REACTIONS OF 4-PYRIMIDONES - STRUCTURES AND PROPERTIES OF THE BETA-LACTAMS FORMED

被引：21

作者：

HIROKAMI, S

HIRAI, Y

NAGATA, M

机构：

[1] TOYAMA MED & PHARMACEUT UNIV,CHEM LAB,SUGITANI,TOYAMA 93001,JAPAN

[2] TOYAMA MED & PHARMACEUT UNIV,FAC PHARMACEUT SCI,SUGITANI,TOYAMA 93001,JAPAN

[3] TANABE SEIYAKU CO LTD,CHEM RES LAB,TODA,SAITAMA 335,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 13期

关键词：

D O I：

10.1021/jo01327a008

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The photochemistry of substituted 4-pyrimidone derivatives 1, 3, 5, and 6 was studied in alcoholic solution. Upon irradiation, the fused 4-pyrimidones 1 and 2, 3, 6-trialkyl-4-pyrimidone 3 gave (aminoalkylidenel-d-alkoxy-.d-lactams 2 and 4, respectively. On the other hand, the substituted 4-pyrimidones 5 and 6 did not afford any products with properties expected of iV-alkyl-2-azetidinone. The structure of 2a was confirmed by X-ray crystallographic analysis. The geometrical isomerization about the double bond of the d-lactams obtained was also discussed. © 1979, American Chemical Society. All rights reserved.

引用

页码：2083 / 2087

页数：5

共 23 条

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AHLBRECHT H, 1969, TETRAHEDRON LETT, P439

[3] STEREOCHEMISTRY OF BETA-LACTAMS DERIVED FROM ALPHA-KETO-GAMMA-LACTAMS BY RING CONTRACTION - X-RAY ANALYSIS AND DIFFERENTIAL BEHAVIOR WITH SHIFT-REAGENTS OF DIFUNCTIONAL BETA-LACTAMS [J].