QUANTITATIVE ASPECTS OF NORMAL LOCOMOTION IN RATS

被引:146
作者
HRUSKA, RE
KENNEDY, S
SILBERGELD, EK
机构
[1] Experimental Therapeutics Branch NINCDS, NIH Bethesda, MD
关键词
D O I
10.1016/0024-3205(79)90389-8
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The basic quantitative aspects of walking are described for a group of normal rats. Within the range of speed from 20 to 80 cm/sec, rats walk consistently with no spatial or temporal alterations. All four feet show similar walking parameters. Walking can be described spatially, in terms of placement of the four feet, and temporally, in terms of stride duration and of its two components, swing time and stance time. As rats walk more quickly, their stance time decreases, while their stride length increases. The swing time does not change with speed of walking. Normal gait is a lateral sequence, diagonal couplet. This sequencing does not vary with speed of locomotion within the range for walking. The ability to quantify normal rat locomotion permits precise description of the locomotion dysfunction observed in animal models of neurological diseases. © 1979.
引用
收藏
页码:171 / 179
页数:9
相关论文
共 15 条
  • [1] SIMPLE RECORDING GRIP STRENGTH DEVICE
    CABE, PA
    TILSON, HA
    MITCHELL, CL
    DENNIS, R
    [J]. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1978, 8 (01) : 101 - 102
  • [2] MUSCLE-ACTIVITY IN RAT LOCOMOTION - MOVEMENT ANALYSIS AND ELECTROMYOGRAPHY OF FLEXORS AND EXTENSORS OF ELBOW
    COHEN, AH
    GANS, C
    [J]. JOURNAL OF MORPHOLOGY, 1975, 146 (02) : 177 - 196
  • [3] WATER UPTAKE, DIAMETER CHANGE, AND NONLINEAR DIFFUSION IN TREE STEMS
    PARLANGE, JY
    TURNER, NC
    WAGGONER, PE
    [J]. PLANT PHYSIOLOGY, 1975, 55 (02) : 247 - 250
  • [4] SCALING STRIDE FREQUENCY AND GAIT TO ANIMAL SIZE - MICE TO HORSES
    HEGLUND, NC
    TAYLOR, CR
    MCMAHON, TA
    [J]. SCIENCE, 1974, 186 (4169) : 1112 - 1113
  • [5] Hildebrand M., 1966, Folia Biotheoretica, VNo. 6, P9
  • [6] METHOD FOR MECHANO-GRAPHICAL RECORDING OF MUSCLE TONE IN RAT - EFFECT OF SOME ANTI-PARKINSONIAN DRUGS ON RIGIDITY INDUCED BY RESERPINE
    JOHNELS, B
    STEG, G
    UNGERSTEDT, U
    [J]. BRAIN RESEARCH, 1978, 140 (01) : 177 - 181
  • [7] ANALYSIS OF PARKINSONIAN GAIT
    KNUTSSON, E
    [J]. BRAIN, 1972, 95 : 475 - &
  • [8] REINFORCEMENT INFLUENCES UPON TOPOGRAPHY OF TREADMILL LOCOMOTION BY CATS
    LOCKARD, DE
    TRAHER, LM
    WETZEL, MC
    [J]. PHYSIOLOGY & BEHAVIOR, 1976, 16 (02) : 141 - 146
  • [9] LOCOMOTOR DAMAGE IN RATS AFTER X-IRRADIATION INUTERO
    MULLENIX, P
    NORTON, S
    CULVER, B
    [J]. EXPERIMENTAL NEUROLOGY, 1975, 48 (02) : 310 - 324
  • [10] PETERSON CR, 1972, AMER J PHYSICAL MED, V51, P171