PROXIMAL CHARGE EFFECTS ON COORDINATION OF HISTAMINE BY AQUOCYANOCOBINAMIDE

被引：6

作者：

MARQUES, HM

机构：

来源：

INORGANICA CHIMICA ACTA | 1990年 / 174卷 / 02期

关键词：

D O I：

10.1016/S0020-1693(00)80311-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Coordination of histamine by aquocyanocobinamide (25 °C, μ = 1 M) causes a decrease in the pKa of the pendant amino group of the ligand from 9.96 to 9.02 and of the endocyclic imino group from >14 to 11.34. This system provides an example of the perturbation of the acid dissociation constants of ionisable functional groups by a proximal charge interaction with the residual positive charge on the metal centre. © 1990.

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页码：271 / 273

页数：3

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