FALSIFICATIONISM AND CLINICAL-TRIALS

被引：30

作者：

SENN, SJ

机构：

[1] Medical Department, Pharmaceuticals Division, Ciba-Geigy Ag, Basle

来源：

STATISTICS IN MEDICINE | 1991年 / 10卷 / 11期

关键词：

D O I：

10.1002/sim.4780101106

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The relevance of the philosophy of Sir Karl Popper to the planning, conduct and analysis of clinical trials is examined. It is shown that blinding and randomization can only be regarded as valuable for the purpose of refuting universal hypotheses. The purpose of inclusion criteria is also examined. It is concluded that a misplaced belief in induction is responsible for many false notions regarding clinical trials.

引用

页码：1679 / 1692

页数：14

共 37 条

[1]

Popper K., A Pocket Popper, (1983)

[2]

Quinton A., Induction, The Fontana Dictionary of Modern Thought, (1977)

[3]

Vesey G., Foulkes P., Dictionary of Philosophy, (1990)

[4]

Urmson J.O., Deduction, The Concise Encyclopedia of Western Philosophy and Philosophers, (1989)

[5]

Hume D., A Treatise of Human Nature, (1984)

[6]

Hume D., An enquiry concerning human understanding, The Empiricists, (1974)

[7]

Mike V., Philosophers assess randomized clinical trials: the need for dialogue, Controlled Clinical Trials, 10, pp. 244-253, (1989)

[8]

Popper K., Popper Selections, (1985)

[9]

Causal Inference, (1988)

[10]

Briskman L., Doctors and witchdoctors: which doctors are which?, British Medical Journal, 295, pp. 1108-1110, (1987)

← 1 2 3 4 →