Bark and wood of Ocotea porosa contained eight new bicyclo [3.2.1]octanoid neolignans belonging to the rel-(1'R,4'S,5'R,7S,8R)-DELTA(2',8')-4'-acetoxy-6'-oxo-8.1',7.5'-neolignan, the rel-(1'R,4'R,5'R,7R,8S)-DELTA(2',8')-4'-acetoxy-6'-oxo-8.1',7.5'-neolignan and the rel-(1'R,5'S,6'R,7S,8R)-DELTA(2',8')-3',5'-dioxy-4'-oxo-8.1',7.5'-neolignan series.