EQUILIBRIUM - INTRACELLULAR-DISTRIBUTION OF STEROID-RECEPTORS

被引：171

作者：

SHERIDAN, PJ

BUCHANAN, JM

ANSELMO, VC

MARTIN, PM

机构：

[1] Department of Anatomy, University of Texas, Health Science Center at San Antonio, San Antonio, TX 78284

[2] Laboratoire Recepteurs Hormonaux, Institut Paoli Calmette, Marseilles

来源：

NATURE | 1979年 / 282卷 / 5739期

关键词：

D O I：

10.1038/282579a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Data are presented which suggest that there are unbound receptors for oestrogen in nuclei of the smooth muscle cells of the myometrium. A new model for the distribution of unbound receptors is proposed in which unbound receptor is in equilibrium, partitioned between nucleus and cytoplasm according to the free water content of these intracellular compartments. © 1979 Nature Publishing Group.

引用

页码：579 / 582

页数：4

共 18 条

[1] ESTRADIOL BINDING OF EXCEPTIONALLY HIGH AFFINITY BY A NONHISTONE CHROMATIN PROTEIN FRACTION [J].