PROTEIN FOLDING[--]UNFOLDING DYNAMICS

被引：56

作者：

DAGGETT, V ^{[1
]}

LEVITT, M ^{[1
]}

机构：

[1] STANFORD UNIV,DEPT CELL BIOL,STANFORD,CA 94305

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1994年 / 4卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-440X(94)90322-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

There have been significant experimental advances in the field of protein folding in the past two to three years, and realistic simulation of protein denaturation is now becoming a reality. These approaches are complementary, in that there are inherent limitations to detailed experimental structural characterization of folding intermediates, and simulations can aid in overcoming these.

引用

页码：291 / 295

页数：5

共 32 条

[1] SOLUTION CONFORMATIONS AND AGGREGATIONAL PROPERTIES OF SYNTHETIC AMYLOID BETA-PEPTIDES OF ALZHEIMERS-DISEASE - ANALYSIS OF CIRCULAR-DICHROISM SPECTRA
BARROW, CJ
YASUDA, A
KENNY, PTM
ZAGORSKI, MG
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1992, 225 (04) : 1075 - 1093
[2] CHARACTERIZATION OF NATIVE APOMYOGLOBIN BY MOLECULAR-DYNAMICS SIMULATION
BROOKS, CL
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1992, 227 (02) : 375 - 380
[3] HYDRATION OF PROTEINS - A COMPARISON OF EXPERIMENTAL RESIDENCE TIMES OF WATER-MOLECULES SOLVATING THE BOVINE PANCREATIC TRYPSIN-INHIBITOR WITH THEORETICAL-MODEL CALCULATIONS
BRUNNE, RM
LIEPINSH, E
OTTING, G
WUTHRICH, K
VANGUNSTEREN, WF
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1993, 231 (04) : 1040 - 1048
[4] CHARACTERIZATION OF HYDROPHOBIC CORES IN APOMYOGLOBIN - A PROTON NMR-SPECTROSCOPY STUDY
COCCO, MJ
LECOMTE, JTJ
[J]. BIOCHEMISTRY, 1990, 29 (50) : 11067 - 11072
[5] CREIGHTON TE, 1978, PROG BIOPHYS MOL BIO, V33, P231
[6] A MODEL OF THE MOLTEN GLOBULE STATE FROM MOLECULAR-DYNAMICS SIMULATIONS
DAGGETT, V
LEVITT, M
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (11) : 5142 - 5146
[7] A MOLECULAR-DYNAMICS SIMULATION OF THE C-TERMINAL FRAGMENT OF THE L7/L12 RIBOSOMAL-PROTEIN IN SOLUTION
DAGGETT, V
LEVITT, M
[J]. CHEMICAL PHYSICS, 1991, 158 (2-3) : 501 - 512
[8] PROTEIN UNFOLDING PATHWAYS EXPLORED THROUGH MOLECULAR-DYNAMICS SIMULATIONS
DAGGETT, V
LEVITT, M
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1993, 232 (02) : 600 - 619
[9] REALISTIC SIMULATIONS OF NATIVE-PROTEIN DYNAMICS IN SOLUTION AND BEYOND
DAGGETT, V
LEVITT, M
[J]. ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 1993, 22 : 353 - 380
[10] DAGGETT V, 1993, TECHNIQUES PROTEIN C, V4, P525

← 1 2 3 4 →