THE ID GENE IS ACTIVATED BY SERUM BUT IS NOT REQUIRED FOR DEDIFFERENTIATION IN RAT VASCULAR SMOOTH-MUSCLE CELLS

被引：30

作者：

KEMP, PR

GRAINGER, DJ

SHANAHAN, CM

WEISSBERG, PL

METCALFE, JC

机构：

[1] UNIV CAMBRIDGE,ADDENBROOKES HOSP,SCH CLIN MED,CAMBRIDGE CB2 2QQ,ENGLAND

[2] UNIV CAMBRIDGE,DEPT BIOCHEM,CAMBRIDGE CB2 2PJ,ENGLAND

来源：

BIOCHEMICAL JOURNAL | 1991年 / 277卷

基金：

英国惠康基金;

关键词：

D O I：

10.1042/bj2770285

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Primary rat vascular smooth muscle cells cultured on fibronectin in the absence of serum lost smooth-muscle-specific myosin heavy chain but did not enter the cell cycle and proliferate until they were stimulated by serum. Under these conditions accumulation of Id mRNA occurred only in response to serum and was maximal during the G1 phase of the cycle.

引用

页码：285 / 288

页数：4

共 14 条

[1] THE PROTEIN ID - A NEGATIVE REGULATOR OF HELIX-LOOP-HELIX DNA-BINDING PROTEINS
BENEZRA, R
DAVIS, RL
LOCKSHON, D
TURNER, DL
WEINTRAUB, H
[J]. CELL, 1990, 61 (01) : 49 - 59
[2] SMOOTH-MUSCLE CELL IN CULTURE
CHAMLEYCAMPBELL, J
CAMPBELL, GR
ROSS, R
[J]. PHYSIOLOGICAL REVIEWS, 1979, 59 (01) : 1 - 61
[3] ACTIN EXPRESSION IN SMOOTH-MUSCLE CELLS OF RAT AORTIC INTIMAL THICKENING, HUMAN ATHEROMATOUS PLAQUE, AND CULTURED RAT AORTIC MEDIA
GABBIANI, G
KOCHER, O
BLOOM, WS
VANDEKERCKHOVE, J
WEBER, K
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1984, 73 (01) : 148 - 152
[4] EXPRESSION OF NONMUSCLE MYOSIN HEAVY AND LIGHT-CHAINS IN SMOOTH-MUSCLE
GAYLINN, BD
EDDINGER, TJ
MARTINO, PA
MONICAL, PL
HUNT, DF
MURPHY, RA
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1989, 257 (05): : C997 - C1004
[5] A LARGE ACCUMULATION OF NONMUSCLE MYOSIN OCCURS AT 1ST ENTRY INTO M-PHASE IN RAT VASCULAR SMOOTH-MUSCLE CELLS
GRAINGER, DJ
HESKETH, TR
METCALFE, JC
WEISSBERG, PL
[J]. BIOCHEMICAL JOURNAL, 1991, 277 : 145 - 151
[6] GROSCHELSTEWART U, 1975, CELL TISSUE RES, V165, P13
[7] KAWAMOTO S, 1987, J BIOL CHEM, V262, P7282
[8] MYOGENIC PROGRAMS OF MOUSE MUSCLE-CELL LINES - EXPRESSION OF MYOSIN HEAVY-CHAIN ISOFORMS, MYOD1, AND MYOGENIN
MILLER, JB
[J]. JOURNAL OF CELL BIOLOGY, 1990, 111 (03) : 1149 - 1159
[9] MOSSE PRL, 1985, LAB INVEST, V53, P556
[10] EXPRESSION OF SMOOTH-MUSCLE SPECIFIC ALPHA-ISOACTIN IN CULTURED VASCULAR SMOOTH-MUSCLE CELLS - RELATIONSHIP BETWEEN GROWTH AND CYTODIFFERENTIATION
OWENS, GK
LOEB, A
GORDON, D
THOMPSON, MM
[J]. JOURNAL OF CELL BIOLOGY, 1986, 102 (02) : 343 - 352

← 1 2 →