ULTRASONOGRAPHIC FETAL SPLEEN MEASUREMENTS IN RED-BLOOD-CELL ALLOIMMUNIZED PREGNANCIES

被引：50

作者：

OEPKES, D ^{[1
]}

MEERMAN, RH ^{[1
]}

VANDENBUSSCHE, FPHA ^{[1
]}

VANKAMP, IL ^{[1
]}

KOK, FG ^{[1
]}

KANHAI, HHH ^{[1
]}

机构：

[1] LEIDEN UNIV,DEPT MED STAT,2300 RA LEIDEN,NETHERLANDS

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1993年 / 169卷 / 01期

关键词：

FETAL SPLEEN; PRENATAL ULTRASONOGRAPHY; RED BLOOD CELL ALLOIMMUNIZATION; BLOOD GROUP INCOMPATIBILITY; INTRAUTERINE TRANSFUSION;

D O I：

10.1016/0002-9378(93)90145-9

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

OBJECTIVES: This study was performed to evaluate the possible relationship between fetal spleen size and fetal hemoglobin levels and to assess the predictive value of ultrasonographically measured fetal spleen size as an estimate of the severity of fetal hemolytic anemia. STUDY DESIGN: Before 85 consecutive fetal blood samples in 28 red blood cell-alloimmunized pregnancies ultrasonographic fetal spleen measurements were performed. Results were compared with our own longitudinally derived reference ranges and were correlated with fetal hemoglobin deficit. RESULTS: A significant positive correlation was found between spleen perimeter and fetal hemoglobin deficit. The ultrasonographic finding of splenomegaly correctly predicted severe fetal anemia (hemoglobin deficit > 5 SD from normal mean) in 44 of 47 cases, a positive predictive value of 94%. At first transfusion ail fetuses showing splenomegaly were severely anemic. CONCLUSION: Fetal spleen measurements may be a useful adjunct to ultrasonographic evaluation in the management of severe red blood cell-alloimmunized pregnancies.

引用

页码：121 / 128

页数：8

共 23 条

[1]

AICKIN M, 1986, J ROY STAT SOC, V149, P1

[2] ACUTE FETAL DISTRESS ASSOCIATED WITH PERCUTANEOUS UMBILICAL BLOOD-SAMPLING [J].