ALKYLATING AGENTS IN BRONCHOGENIC CARCINOMA

被引:345
作者
GREEN, RA
HUMPHREY, E
CLOSE, H
PATNO, ME
机构
关键词
D O I
10.1016/0002-9343(69)90071-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A large number of patients in a group of Veterans Administration Hospitals received a variety of alkylating agents in studies in which these agents were randomized with an inert compound. Intravenous cyclophosphamide, and possibly nitrogen mustard, had a slight favorable influence upon survival for all patients. A difference between the two agents was seen: patients with squamous cell carcinoma appeared to respond best to nitrogen mustard therapy and patients with small cell undifferentiated carcinoma to cyclophosphamide therapy, in fairly striking fashion. Over-all influences upon survival, however, were not remarkable. © 1969.
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页码:516 / +
页数:1
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