H-1 AND C-13-NMR STUDY OF SOME CIS-[PT(NH3)2X2]Y2 COMPLEXES (X = IMIDAZOLES, PYRIMIDINES, 3-SUBSTITUTED PYRIDINES, INOSINE AND GUANOSINE - Y= CL-, CLO4- IN AQUEOUS-SOLUTIONS

195Pt1H and 195Pt13C coupling constants are reported for species of the type cis-[PtNH3)2X2]Y2. When X is an imidazole or subsituted imidazole two and three bond coupling to ring carbon nuclei are observed and the two 2J couplings are significantly differenct in size. When Pt is coordinated to an imidazole ring fused to a second ring as in benzimidazole or the purine nucleosides a similar pattern of coupling is observed. In general the trend is 2JC2 > 3J>2JC4. In none of the substituted pyridine complexes was a 2J observed. 3J was very sensitive to the nature of the substituent on the observed nucleus. In most cases a 4J of ca. 11 Hz was observed. Coupling in pyrimidine complexes to C nuclei was more extensive and 2J, 3J and 4J coupling is observed. It has been shown that water is a far superior solvent to DMSO and yields narrower resonances and thus the possibility of observing smaller coupling constants. In DMSO most of the complexes studied also displayed some solvolysis. © 1979.