EEG COHERENCE IN ALZHEIMER-DISEASE

被引：180

作者：

BESTHORN, C

FORSTL, H

GEIGERKABISCH, C

SATTEL, H

GASSER, T

SCHREITERGASSER, U

机构：

[1] Zentralinstitut für Seelische Gesundheit, 68159 Mannheim

来源：

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1994年 / 90卷 / 03期

关键词：

COHERENCE; QUANTITATIVE EEG; ALZHEIMER DISEASE; DEMENTIA; NORMAL CONTROLS;

D O I：

10.1016/0013-4694(94)90095-7

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A novel approach is introduced to examine EEG coherence in different frequency bands of 17 locations from the 10-20 system. Fifty patients with clinically diagnosed Alzheimer's disease were compared with 42 age-approximated non-demented controls. We determined the average coherence between individual electrodes and all neigbouring electrodes. Coherence was decreased in the sample of demented patients and this effect was most pronounced in the frontal and central derivations of the theta, alpha and beta frequency bands. The results can be interpreted as the effects of neuronal loss and neocortical disconnection.

引用

页码：242 / 245

页数：4

共 32 条

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[2]

BAGGIO C, 1991, ALZHEIMERS DISEASE B

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