SYNTHESIS OF OLIGONUCLEOTIDE PHOSPHORODITHIOATES

被引:30
作者
BEATON, G [1 ]
BRILL, WKD [1 ]
GRANDAS, A [1 ]
MA, YX [1 ]
NIELSEN, J [1 ]
YAU, E [1 ]
CARUTHERS, MH [1 ]
机构
[1] UNIV COLORADO,DEPT CHEM & BIOCHEM,BOULDER,CO 80309
关键词
D O I
10.1016/S0040-4020(01)81775-0
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of DNA containing sulfur at the two nonbonding internucleotide valencies is reported. Several different routes using either tervalent or pentavalent mononucleotide synthons are described.
引用
收藏
页码:2377 / 2388
页数:12
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