ACTIVATORS AND EFFECTORS OF RAS P21 PROTEINS

被引：217

作者：

MCCORMICK, F

机构：

[1] F McCormick, Onyx Pharmaceuticals, Richmond, CA 94806

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 01期

关键词：

D O I：

10.1016/0959-437X(94)90093-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Over the past year, major advances have been made in understanding the key steps involved in signaling pathways-from receptor tyrosine kinases to ras p21, and on to a cascade of serine/threonine kinases. A chain of specific protein-protein interactions is responsible for signal transduction. Components of the pathway are highly conserved between flies, nematodes and mammals, and constitute a primary signaling device in most cell types.

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页码：71 / 76

页数：6

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