Metabolism of daidzein and genistein by intestinal bacteria

被引：149

作者：

Chang, YC

Nair, MG

机构：

[1] MICHIGAN STATE UNIV,DEPT HORT,BIOACT NAT PROD LAB,E LANSING,MI 48824

[2] MICHIGAN STATE UNIV,PESTICIDE RES CTR,E LANSING,MI 48824

来源：

JOURNAL OF NATURAL PRODUCTS | 1995年 / 58卷 / 12期

关键词：

D O I：

10.1021/np50126a014

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The isoflavones daidzein [1] and genistein [2] were fermented with human fecal bacteria under anaerobic conditions. Dihydrodaidzein [3], benzopyran-4,7-diol,3-(4-hydroxyphenyl) [4], and equol [5] were isolated from the fermentation broth of 1. Only one metabolite, dihydrogenistein [6], was isolated and characterized from the fermentation broth of 2. Metabolites 3-6 were identified by spectral methods.

引用

页码：1892 / 1896

页数：5

共 23 条

[1]

AKIYAMA T, 1987, J BIOL CHEM, V262, P5592

[2]

ALDERCREUTZ H, 1986, CLIN CHIM ACTA, V158, P147

[3]

ALDERCREUTZ H, 1988, FRONTIERS GASTROINTE, V14, P165

[4] THE IDENTIFICATION OF THE WEAK ESTROGEN EQUOL [7-HYDROXY-3-(4'-HYDROXYPHENYL)CHROMAN] IN HUMAN-URINE [J].