THE BASEMENT-MEMBRANE AT THE NEUROMUSCULAR-JUNCTION - A SYNAPTIC MEDIATRIX

被引：35

作者：

CARBONETTO, S

LINDENBAUM, M

机构：

[1] Centre for Neuroscience Research, McGill University, Montreal General Hospital Research Institute, Montreal, Que. H3G 1A4

来源：

CURRENT OPINION IN NEUROBIOLOGY | 1995年 / 5卷 / 05期

关键词：

D O I：

10.1016/0959-4388(95)80064-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The basement membrane at the neuromuscular junction directs formation of pre- and postsynaptic elements at this synapse. Efforts to understand the molecular basis for development of the postsynaptic specialization have brought new insights into extracellular matrix proteins and their cell-surface receptors. Recent evidence for an agrin receptor and mice null for the s-laminin gene have reinforced the function of the basement membrane in both orthograde and retrograde signalling across the synapse.

引用

页码：596 / 605

页数：10

共 64 条

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