DIASTEREOSELECTIVE REDUCTION OF ALPHA-KETO ESTERS BEARING CHIRO-INOSITOL DERIVATIVES AS CHIRAL AUXILIARIES

被引：51

作者：

AKIYAMA, T ^{[1
]}

NISHIMOTO, H ^{[1
]}

OZAKI, S ^{[1
]}

机构：

[1] EHIME UNIV, FAC ENGN, DEPT RESOURCES CHEM, BUNKYO CHO, MATSUYAMA, EHIME 790, JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(00)79661-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reduction of alpha-keto esters derived from (1L)-1,2;5, 6-biscyclohexylidene-3-tert-butyldimethysilyl-chiro-inositol with Selectride(R) proceeded with high diastereoselectivity to afford the corresponding alpha-hydroxy esters. Addition of 18-Crown-6 led to dramatic changeover in diastereofacial selectivity.

引用

页码：1335 / 1338

页数：4

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