TRANSLOCATION 1-7 IN HEMATOLOGIC DISORDERS - A REPORT OF 3 FURTHER CASES - ABSENCE OF AMPLIFICATION OF THE GENE FOR THE EPIDERMAL GROWTH-FACTOR RECEPTOR

被引：9

作者：

ABRAHAMSON, GM

RACK, K

BUCKLE, VJ

OSCIER, DG

KELLY, S

WAINSCOAT, JS

机构：

[1] JOHN RADCLIFFE HOSP,DEPT HAEMATOL,LEUKAEMIA RES FUND,MOLEC & CYTOGENET HAEMATOL UNIT,OXFORD OX3 9DU,ENGLAND

[2] ROYAL VICTORIA HOSP,DEPT HAEMATOL,BOURNEMOUTH,DORSET,ENGLAND

[3] WYCOMBE GEN HOSP,DEPT HAEMATOL,HIGH WYCOMBE,BUCKS,ENGLAND

来源：

CANCER GENETICS AND CYTOGENETICS | 1991年 / 53卷 / 01期

关键词：

D O I：

10.1016/0165-4608(91)90118-E

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report three new cases with a hematologic disorder and the unbalanced translocation der(1)t(1;7)(p11;p11). It has been speculated that the gene for the epidermal growth factor receptor, localized to the short arm of chromosome 7, might be amplified in cases with this translocation. We have demonstrated that there is no amplification of this gene in these three cases.

引用

页码：91 / 95

页数：5

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