AN ASYMMETRIC-SYNTHESIS OF D-1,6-DIEPICASTANOSPERMINE

被引：28

作者：

BURGESS, K

CHAPLIN, DA

机构：

[1] Department of Chemistry Texas A, M University College Station

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 41期

关键词：

CASTANOSPERMINE; 1,6,7,8-TETRAHYDROXYINDOLIZIDINE; GLUCOSIDASE INHIBITOR;

D O I：

10.1016/S0040-4039(00)60010-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

D-1,6-Diepicastanospemine has been prepared via reaction of an allylstannane with the arabinose derivative 1a. This reaction was almost 100 % stereoselective, but the corresponding allylations of aldehydes 1b - d gave mixtures of isomers. Variable stereodifferentiation in these reactions can be attributed to the influence of the distal (gamma) chiral center.

引用

页码：6077 / 6080

页数：4

共 23 条

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