INHIBITION OF TOXOPLASMA-GONDII PROTEIN-SYNTHESIS BY AZITHROMYCIN

被引：32

作者：

BLAIS, J

GARNEAU, V

CHAMBERLAND, S

机构：

[1] UNIV LAVAL,CTR HOSP,CTR RECH,INFECTIOL LAB & SERV,QUEBEC CITY G1V 4G2,QUEBEC,CANADA

[2] UNIV LAVAL,FAC MED,DEPT MICROBIOL,QUEBEC CITY G1V 4G2,QUEBEC,CANADA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 08期

关键词：

D O I：

10.1128/AAC.37.8.1701

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Azithromycin was shown to specifically inhibit the protein synthesis of Toxoplasma gondii in experimental systems by using free tachyzoites and T. gondii-infected mouse macrophages. RNA synthesis of the parasite was not affected by azithromycin. Inhibition of protein synthesis was also proportional to the relative anti-Toxoplasma activity of three macrolides.

引用

页码：1701 / 1703

页数：3

共 12 条

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