EPOXYMURIN-A AND EPOXYMURIN-B, 2 BIOGENETIC PRECURSORS OF ANNONACEOUS ACETOGENINS FROM ANNONA-MURICATA

被引：36

作者：

HISHAM, A

SREEKALA, U

PIETERS, L

DEBRUYNE, T

VANDENHEUVEL, H

CLAEYS, M

机构：

[1] UNIV INSTELLING ANTWERP,DEPT PHARMACEUT SCI,B-2610 WILRIJK,BELGIUM

[2] COLL ENGN,RES CTR,TRIVANDRUM 16,KERALA,INDIA

来源：

TETRAHEDRON | 1993年 / 49卷 / 31期

关键词：

D O I：

10.1016/S0040-4020(01)80433-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

NMR and mass spectroscopic methods have been used for the structure elucidation of two new Annonaceous acetogenin precursor compounds, epoxymurins A and B, isolated from the hexane extract of the stem bark of Annona muricata, together with diepomuricanin and solamin. Epoxymurins A and B provide an important missing link in the proposed biogenetic pathway for acetogenins containing one tetrahydrofuran ring.

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页码：6913 / 6920

页数：8

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