SERTRALINE INTOXICATION IN A CHILD

被引:45
作者
KAMINSKI, CA [1 ]
ROBBINS, MS [1 ]
WEIBLEY, RE [1 ]
机构
[1] TAMPA GEN HOSP,DEPT PHARMACOTHERAPY & RES,POB 1289,TAMPA,FL 33601
关键词
D O I
10.1016/S0196-0644(94)70364-7
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
We describe severe sertraline intoxication in a child after accidental ingestion. Sertraline is a new antidepressant that has potent and selective inhibition of neuronal serotonin reuptake. Drug company-sponsored research has suggested little toxicity for this compound. Our patient exhibited prolonged tachycardia, hypertension, hallucinations, coma, hyperthermia, tremors of all extremities, and skin flushing. Clinicians should consider the possibility of serotonin syndrome among patients with similar clinical features and a recent history of sertraline or other serotonergic agent ingestion.
引用
收藏
页码:1371 / 1374
页数:4
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