USE OF POROUS GRAPHITIZED CARBON COLUMN FOR DETERMINING TAXOL IN TAXUS-BACCATA

被引：13

作者：

FORGACS, E

机构：

[1] Central Research Institute for Chemistry, Hungarian Academy of Sciences, Budapest, 1525

来源：

CHROMATOGRAPHIA | 1994年 / 39卷 / 11-12期

关键词：

COLUMN LIQUID CHROMATOGRAPHY; POROUS GRAPHITIZED CARBON; TAXOL; TAXUS BACCATA;

D O I：

10.1007/BF02274591

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Porous graphitized carbon columns have been used for the separation and quantitative determination of the anticancer drug taxol in the bark and foliage of Taxus baccata. Successful separations were achieved using water: dioxane 54:46 v/v eluent. Peak purity tests and the spectra of taxol peaks taken at different retention times indicated that the taxol peak is not entirely homogeneous and probably contains other taxoteres coeluted with the main compound.

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页码：740 / 742

页数：3

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