DELAYED TREATMENT WITH THE SPIN TRAP ALPHA-PHENYL-N-TERT-BUTYL NITRONE (PBN) REDUCES INFARCT SIZE FOLLOWING TRANSIENT MIDDLE CEREBRAL-ARTERY OCCLUSION IN RATS

被引：167

作者：

ZHAO, Q ^{[1
]}

PAHLMARK, K ^{[1
]}

SMITH, ML ^{[1
]}

SIESJO, BK ^{[1
]}

机构：

[1] LUND UNIV,EXPTL BRAIN RES LAB,S-22101 LUND,SWEDEN

来源：

ACTA PHYSIOLOGICA SCANDINAVICA | 1994年 / 152卷 / 03期

关键词：

BRAIN; FOCAL ISCHEMIA; FREE RADICALS; ALPHA-PHENYL-N-TERT-BUTYL NITRONE; RATS;

D O I：

10.1111/j.1748-1716.1994.tb09816.x

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

[No abstract available]

引用

页码：349 / 350

页数：2

共 9 条

[1] ALPHA-PHENYL-TERT-BUTYL-NITRONE REDUCES CORTICAL INFARCT AND EDEMA IN RATS SUBJECTED TO FOCAL ISCHEMIA [J].

CAO, XH ;

PHILLIS, JW .

BRAIN RESEARCH, 1994, 644 (02) :267-272

[2] PROTECTION AGAINST OXIDATIVE DAMAGE TO CNS BY ALPHA-PHENYL-TERT-BUTYL NITRONE (PBN) AND OTHER SPIN-TRAPPING AGENTS - A NOVEL SERIES OF NONLIPID FREE-RADICAL SCAVENGERS [J].

CARNEY, JM ;

FLOYD, RA .

JOURNAL OF MOLECULAR NEUROSCIENCE, 1991, 3 (01) :47-57

[3] THE FREE-RADICAL TRAPPING AGENT N-TERT-BUTYL-ALPHA-PHENYLNITRONE (PBN) ATTENUATES CEREBRAL ISCHEMIC-INJURY IN GERBILS [J].

CLOUGHHELFMAN, C ;

PHILLIS, JW .

FREE RADICAL RESEARCH COMMUNICATIONS, 1991, 15 (03) :177-186

[4] ROLE OF OXYGEN FREE-RADICALS IN CARCINOGENESIS AND BRAIN ISCHEMIA [J].

FLOYD, RA .

FASEB JOURNAL, 1990, 4 (09) :2587-2597

[5] DOES ISCHEMIA WITH REPERFUSION LEAD TO OXIDATIVE DAMAGE TO PROTEINS IN THE BRAIN [J].

FOLBERGROVA, J ;

KIYOTA, Y ;

PAHLMARK, K ;

MEMEZAWA, H ;

SMITH, ML ;

SIESJO, BK .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1993, 13 (01) :145-152

[6] OXIDATIVE DAMAGE TO BRAIN PROTEINS, LOSS OF GLUTAMINE-SYNTHETASE ACTIVITY, AND PRODUCTION OF FREE-RADICALS DURING ISCHEMIA REPERFUSION-INDUCED INJURY TO GERBIL BRAIN [J].

OLIVER, CN ;

STARKEREED, PE ;

STADTMAN, ER ;

LIU, GJ ;

CARNEY, JM ;

FLOYD, RA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (13) :5144-5147

[7] EFFECTS OF DIMETHYLTHIOUREA ON SELECTIVE NEURONAL VULNERABILITY IN FOREBRAIN ISCHEMIA IN RATS [J].

PAHLMARK, K ;

FOLBERGROVA, J ;

SMITH, ML ;

SIESJO, BK .

STROKE, 1993, 24 (05) :731-736

[8] THE OMEGA-CONOPEPTIDE SNX-111, AN N-TYPE CALCIUM-CHANNEL BLOCKER, DRAMATICALLY AMELIORATES BRAIN-DAMAGE DUE TO TRANSIENT FOCAL ISCHEMIA [J].

ZHAO, Q ;

SMITH, ML ;

SIESJO, BK .

ACTA PHYSIOLOGICA SCANDINAVICA, 1994, 150 (04) :459-461

[9] HYPERTHERMIA COMPLICATES MIDDLE CEREBRAL-ARTERY OCCLUSION INDUCED BY AN INTRALUMINAL FILAMENT [J].

ZHAO, Q ;

MEMEZAWA, H ;

SMITH, ML ;

SIESJO, BK .

BRAIN RESEARCH, 1994, 649 (1-2) :253-259

← 1 →