T-CELL RESPONSES TO THE TRYPANOSOME VARIANT SURFACE GLYCOPROTEIN - A NEW PARADIGM

被引：38

作者：

MANSFIELD, JM

机构：

[1] John Mansfield is at the Laboratory of Immunology, Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, Madison, WI 53706

来源：

PARASITOLOGY TODAY | 1994年 / 10卷 / 07期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0169-4758(94)90143-0

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

During the past decade, extensive knowledge has been gained with respect to the cellular and molecular mechanisms associated with variant surface glycoprotein (VSG) gene switching in trypanosomes. However, comparatively little is known about the cellular and molecular factors that regulate the host B-cell response to VSG determinants during infection. Here, John Mansfield reflects on the nature of this response.

引用

页码：267 / 270

页数：4

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