STRUCTURAL DETERMINATION OF ASCORBIC-ACID 2-O-PHOSPHATE FORMED VIA ACID-HYDROLYSIS OF AN ASCORBIC-ACID 3-O-PHOSPHINATE

被引：35

作者：

JERNOW, J

BLOUNT, J

OLIVETO, E

PERROTTA, A

ROSEN, P

TOOME, V

机构：

[1] Department of Chemical Research, Hoffmann-La Roche Inc., Nutley

来源：

TETRAHEDRON | 1979年 / 35卷 / 12期

关键词：

D O I：

10.1016/0040-4020(79)80033-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis and X-ray structural determination of 3-O-[(bis-morpholino)phosphinyl]-5,6-O-isopropylidene-l-ascorbate (9) are described. Acid-catalyzed hydrolysis of 9 afforded the 2-O-phosphate 6. Definitive structural proof of 6 is based on a study of the pH profile of its UV spectra as compared with those of ascorbic esters, 2 and 9 (Figs. 1-3). © 1979.

引用

页码：1483 / 1486

页数：4

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