THE RELATIONSHIP BETWEEN COLONIZATION, SECRETOR STATUS AND INVITRO ADHESION OF CANDIDA-ALBICANS TO BUCCAL EPITHELIAL-CELLS FROM DIABETICS

被引:65
作者
DARWAZEH, AMG [1 ]
LAMEY, PJ [1 ]
SAMARANAYAKE, LP [1 ]
MACFARLANE, TW [1 ]
FISHER, BM [1 ]
MACRURY, SM [1 ]
MACCUISH, AC [1 ]
机构
[1] GLASGOW ROYAL INFIRM,DIABET CLIN,GLASGOW G4 0SF,SCOTLAND
关键词
D O I
10.1099/00222615-33-1-43
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
This study investigated whether oral candida infection in diabetics and adhesion of Candida albicans to buccal epithelial cells in vitro were related. Buccal cells from 50 patients with diabetes mellitus showed a significant increase in adhesion of C. albicans strain CDS 88 compared with those collected from 50 non-diabetic controls matched for age, sex and denture status. Oral candida carriage, candida infection and secretor status were also investigated in both groups. The frequency of carriage was increased, but not significantly, and there was a significantly higher incidence of candida infection in diabetic patients compared with controls. Diabetic patients who were non-secretors had a significantly increased frequency of oral candida carriage.
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页码:43 / 49
页数:7
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