NPY-INDUCED INHIBITION OF MALE COPULATORY ACTIVITY IS A DIRECT BEHAVIORAL-EFFECT

被引：26

作者：

POGGIOLI, R

VERGONI, AV

MARRAMA, D

GIULIANI, D

BERTOLINI, A

机构：

[1] Institute of Pharmacology, University of Modena, I-41100 Modena, MO

来源：

NEUROPEPTIDES | 1990年 / 16卷 / 03期

关键词：

D O I：

10.1016/0143-4179(90)90130-Q

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In adult, sexually-experienced male rats, the intracerebroventricular injection of NPY caused a dose-related inhibition of copulatory behaviour, all parameters (mount, intromission and ejaculation latencies, mount and intromission frequences, mean inter-intromission interval, post-ejaculatory interval) being significantly worsened at the dose of 8 μg/rat. Since rats were deprived of food during the behavioural test, it is concluded that inhibition of sexual behaviour is a 'true', direct behavioural effect of NPY, not due to a shift towards increased feeding. © 1990.

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页码：169 / 172

页数：4

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