1,2-DIARYL-4-AMINO-4,5-DIHYDRO-5,5-DISUBSTITUTED IMIDAZOLES - BEHAVIOR IN ACIDIC MEDIUM

被引：4

作者：

CITERIO, L ^{[1
]}

POCAR, D ^{[1
]}

SACCARELLO, ML ^{[1
]}

STRADI, R ^{[1
]}

机构：

[1] UNIV MILANO,FAC FARMA,IST CHIM ORGAN,I-20131 MILANO,ITALY

来源：

TETRAHEDRON | 1979年 / 35卷 / 20期

关键词：

D O I：

10.1016/S0040-4020(01)93753-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The behaviour of 1,2,5-triaryl-4-amino-5-methyl-4,5-dihydro-imidazoles 2a-e and 1,2,5,5-tetraphenyl-4-morpholino-4,5-dihydro-imidazole 2f in acidic medium was studied. By heating in 50% H2SO4, 1,2,4-triaryl-5-methyl-imidazoles and 1,2,4,5-tetraphenyl-imidazole were obtained. When 5-aryl-5-methyl-derivatives were reacted with various nucleophiles in acidic medium the corresponding 4-substituted imidazolines were formed. Generally, only one isomer (viz E) was obtained. The 5,5-diaryl-derivative afforded the 1,2,4,5-tetraphenyl-imidazole even in the presence of nucleophiles. © 1979.

引用

页码：2375 / 2379

页数：5

共 5 条

[1] N-HALOGENOAMIDINES .1. AMINO-IMIDAZOLINES AND AMINO-IMIDAZOLES FROM N-CHLORO-N'-ARYLAMIDINES AND ENAMINES [J].

CITERIO, L ;

POCAR, D ;

STRADI, R ;

GIOIA, B .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1978, (04) :309-314

[2]

DESTRO R, ACTA CRYST

[3]

EVERSET AE, 1911, J CHEM SOC, V99, P1756

[4] MASS-SPECTRA OF SOME 4,5-DIHYDROIMIDAZOLE DERIVATIVES [J].

GIOIA, B ;

CITERIO, L ;

STRADI, R .

ORGANIC MASS SPECTROMETRY, 1978, 13 (06) :319-324

[5]

WEHRLI FW, INTERPRETATION 13C N, pCH2

← 1 →