PURIFICATION OF GAMMA-BENZYL AND GAMMA-METHYL L-GLUTAMATE N-CARBOXYANHYDRIDES BY REPHOSGENATION

被引：48

作者：

DORMAN, LC

SHIANG, WR

MEYERS, PA

机构：

[1] Central Research & Development, Advanced Polymeric Systems Laboratory, The Dow Chemical Co, Midland, MI, 48674

[2] San Ramon, CA, 94583

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 22期

关键词：

D O I：

10.1080/00397919208021140

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Rephosgenation of N-carboxyanhydrides of gamma-benzyl and gamma-methyl L-glutamates, vs multiple recrystallizations, is a very efficient method for obtaining highly purified N-carboxyanhydrides, from which very high MW (0.98-1.5 x 10(6) Daltons) polymers can be derived.

引用

页码：3257 / 3262

页数：6

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