SEXUAL INFLUENCE ON BONE METABOLISM IN UREMIC PATIENTS ON REGULAR DIALYTIC TREATMENT

被引：15

作者：

LUISETTO, G

BERTOLI, M

机构：

[1] UNIV HOSP PADUA,DEPT ENDOCRINOL,PADUA,ITALY

[2] UNIV HOSP PADUA,DEPT NEPHROL,PADUA,ITALY

来源：

NEPHRON | 1994年 / 67卷 / 02期

关键词：

HEMODIALYSIS; PARATHYROID HORMONE; CALCITONIN; BONE GLA PROTEIN; ESTROGENS; BONE SENSITIVITY;

D O I：

10.1159/000187917

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In order to evaluate the influence of sex on bone metabolism in patients on regular dialytic treatment, 82 patients (51 males and 31 females) were studied. All the women were amenorreic and none of them took estrogens. Women showed radiological features of hyperparathyroidism more frequently than men and, in addition, higher bone GLA protein and lower calcitonin serum levels. In both sexes a significant positive correlation was observed between PTH and BGP, but the slope was higher in females, even though not significant. These results suggest that the uremic females show an increased skeletal sensitivity to PTH, probably due to the lack of protective effect of estrogens.

引用

页码：150 / 157

页数：8

共 60 条

[1] COMPARISON OF PARATHYROID-HORMONE ASSAYS WITH BONE HISTOMORPHOMETRY IN RENAL OSTEODYSTROPHY [J].