TWIN-TO-TWIN TRANSFUSION SYNDROME - SELECTIVE FETICIDE BY EMBOLIZATION OF THE HYDROPIC FETUS

被引：35

作者：

DOMMERGUES, M

MANDELBROT, L

DELEZOIDE, AL

AUBRY, MC

FERMONT, L

CAPUTOMAHIEU, D

DUMEZ, Y

机构：

[1] Maternité Port-Royal-Baudelocque, Paris

[2] Service d’Histoembryologie, Hôpital Necker, Paris

[3] Institut de Puériculture, Paris

来源：

FETAL DIAGNOSIS AND THERAPY | 1995年 / 10卷 / 01期

关键词：

TWIN-TO-TWIN TRANSFUSION SYNDROME; SELECTIVE FETICIDE; EMBOLIZATION;

D O I：

10.1159/000264188

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

To improve the outcome of severe twin-to-twin transfusion syndrome with 1 hydropic fetus and to prevent ischemic sequelae in the survivor, we developed a technique of selective feticide by vascular embolization of the most severely damaged twin. Acute second trimester polyhydramnios occurred in 4 biamniotic monochorial twin pregnancies, with 1 fetus normal on ultrasound but the other severely damaged by hydrops and hypertrophic hypokinetic cardiomyopathy. The hydropic fetus underwent embolization using a bolus of histoacryl injected into the umbilical vein and fetal heart under ultrasound guidance. In 1 triplet pregnancy with a set of monochorial fetuses, premature labor occurred at 26 weeks, 2 weeks after embolization, and there were 2 neonatal deaths. The 3 other cases resulted in the birth of a normal infant at 31-37 weeks of gestation. This suggests that in twin-to-twin transfusion syndrome with severe polyhydramnios and hydrops of 1 fetus, embolization may salvage the other twin.

引用

页码：26 / 31

页数：6

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