FLUOROMETRIC METHOD FOR DETERMINATION OF LAPACHOL IN SERUM

被引：10

作者：

FINKEL, JM

HARRISON, SD

机构：

[1] Southern Research Institute, Ninth Ave.

[2] University of Indiana, Birmingham

来源：

ANALYTICAL CHEMISTRY | 1969年 / 41卷 / 13期

关键词：

D O I：

10.1021/ac60282a035

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Lapachol (2-hydroxy-3-(3-methyl-2-butenyl)-l 4-naphthoquinone) was first identified by Hooker (1) and synthesized by Fieser (2). Lapachol and related naphthoquinones have shown antimalarial activity (3) and an influence on oxidative phosphorylation (4), thus preventing the oxidative synthesis of adenosine triphosphate. Lapachol has also shown antitumor activity against Walter-256 tumors (J). © 1969, American Chemical Society. All rights reserved.

引用

页码：1854 / &

共 6 条

[1] The alkylation of hydroxynaphthoquinone. III. A synthesis of lapachol [J].