3-ACETOXYAMINO-2-TRIFLUOROMETHYLQUINAZOLIN-4(3H)ONE AS AN AZIRIDINATING AGENT FOR ALKENES

被引：22

作者：

ATKINSON, RS ^{[1
]}

COOGAN, MP ^{[1
]}

CORNELL, CL ^{[1
]}

机构：

[1] SCHERING AGROCHEM, SAFFRON WALDEN CB10 1XL, ESSEX, ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 15期

关键词：

D O I：

10.1039/c39930001215

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The title compound 4, prepared by lead tetraacetate oxidation of 5, is stable at room temperature and aziridinates alkenes in better yield and higher diastereoselectivity than, e.g. the 2-ethyl compound 1; hydrazinolysis of the quinazolinone ring in 20 gives the corresponding N-aminoaziridine 21 in 64% yield.

引用

页码：1215 / 1216

页数：2

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