STRUCTURE OF 3 ACIDIC O-LINKED CARBOHYDRATE CHAINS OF PORCINE ZONA-PELLUCIDA GLYCOPROTEINS

被引：43

作者：

HOKKE, CH

DAMM, JBL

KAMERLING, JP

VLIEGENTHART, JFG

机构：

[1] UNIV UTRECHT,BIJVOET CTR,DEPT BIOORGAN CHEM,POB 80075,3508 TB UTRECHT,NETHERLANDS

[2] ORGANON INT BV,OSS,NETHERLANDS

来源：

FEBS LETTERS | 1993年 / 329卷 / 1-2期

关键词：

PORCINE ZONA-PELLUCIDA GLYCOPROTEIN; SULFATED N-ACETYLLACTOSAMINE; O-LINKED CARBOHYDRATE CHAIN;

D O I：

10.1016/0014-5793(93)80186-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Structural analysis by 1D and 2D H-1 NMR spectroscopy of three acidic 0-linked oligosaccharide alditols, released from porcine zona pellucida glycoproteins by alkaline borohydride treatment, afforded the following structures: Galbeta1-4(6SO4-)GlcNAcbeta1-3Galbeta1-4GlcNAcbeta1-3Galbeta1-3GalNAc-ol Neu5Gcalpha2-3Galbeta1-4(6SO4-)GlcNAcbeta1-3Galbeta1-4GlcNAcbeta1-3Galbeta1-3GalNAc-ol Neu5Acalpha2-3Galbeta1-4(6SO4-)GIcNAcbeta1-3Galbeta1-4GlcNAcbeta1-3Galbeta1-3GalNAc-ol These oligosaccharides are the smallest compounds that contain the structural elements which are present in the acidic, high-molecular mass O-linked carbohydrate chains of porcine zona pellucida glycoproteins.

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页码：29 / 34

页数：6

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