ANTIINFLAMMATORY EFFECTS OF RECOMBINANT HUMAN MANGANESE SUPEROXIDE-DISMUTASE ON ADJUVANT ARTHRITIS IN RATS

被引：35

作者：

SHINGU, M

TAKAHASHI, S

ITO, M

HAMAMATU, N

SUENAGA, Y

ICHIBANGASE, Y

NOBUNAGA, M

机构：

[1] Department of Clinical Immunology, Medical Institute of Bioregulation, Kyushu University 69, Beppu, 874

来源：

RHEUMATOLOGY INTERNATIONAL | 1994年 / 14卷 / 02期

关键词：

SUPEROXIDE DISMUTASE; RHEUMATOID ARTHRITIS; JOINT DESTRUCTION;

D O I：

10.1007/BF00300251

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The anti-inflammatory effects of recombinant human manganese superoxide dismutase on adjuvant arthritis was investigated. Local application of this manganese superoxide dismutase given every 2 days not only significantly reduced foot swelling but also retarded radiological bone destruction in adjuvant arthritis. Copper zinc superoxide dismutase had little effect on foot swelling.

引用

页码：77 / 81

页数：5

共 23 条

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