GENE-EXPRESSION OF VIP RECEPTOR IN RAT LYMPHOCYTES

被引：44

作者：

GOMARIZ, RP

GARRIDO, E

LECETA, J

MARTINEZ, C

ABALO, R

DELGADO, M

机构：

[1] Departamento Biologia Celular, Facultad de Biologia, Universidad Complutense

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1994年 / 203卷 / 03期

关键词：

D O I：

10.1006/bbrc.1994.2369

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In the present report we analyze by reverse transcription (RT) and polymerase chain reaction (PCR) the expression of vasoactive intestinal peptide receptors (VIP-R) in rat thymocytes and peripheral T and B lymphocytes. We have obtained a specific VIP-R cDNA product of 311 bp identical in size to that obtained from lung. These results have been confirmed by Southern hybridization analysis. VIP receptor gene expression in central and peripheral lymphoid organs support the notion that VIP is a immunomodulatory peptide. (C) 1994 Academic Press, Inc.

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页码：1599 / 1604

页数：6

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