Arthroscopic Technique for Matrix-Induced Autologous Chondrocyte Implantation for the Treatment of Large Chondral Defects in the Knee and Ankle

被引:27
作者
Abelow, Stephen P. [1 ,2 ]
Guillen, Pedro [2 ]
Ramos, Tomas [2 ]
机构
[1] Lake Tahoe Sports Med Ctr, 2311 Lake Tahoe Blvd,Suite 6, South Lake Tahoe, CA 96150 USA
[2] Clin CEMTRO, Unidad Invest Biomed, Madrid, Spain
关键词
MACI; autologous chondrocytes; matrix; collagen membrane; fibrin glue; arthroscopy;
D O I
10.1053/j.oto.2006.08.006
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Matrix/membrane-induced autologous chondrocyte implantation (MACI) is a new biotechnology allowing the impregnation of autologous cultured chondrocytes onto a purified collagen membrane. The MACI implant is fixed with fibrin glue, and little or no suturing is necessary. The procedure can be performed arthroscopically or by miniarthrotomy. The use of magnetic resonance imaging shows progressive signal change with progressive loss of subchondral edema. Histologically a "hyaline-like" cartilage similar to autologous chondrocyte implantation was produced. Specialized instrumentation has been developed to allow for easy arthroscopic implantation of the MACI membrane. (C) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码:257 / 261
页数:5
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