STUDIES RELATING TO THE SYNTHESIS OF THE IMMUNOSUPPRESSIVE AGENT FK-506 - SYNTHESIS OF THE CYCLOHEXYL MOIETY VIA A GROUP-SELECTIVE EPOXIDATION

被引：42

作者：

SCHREIBER, SL

SMITH, DB

机构：

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1989年 / 54卷 / 01期

关键词：

D O I：

10.1021/jo00262a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

收藏

页码：9 / 10

页数：2

相关论文

共 17 条

[1] A DIASTEREOSPECIFIC, NON-RACEMIC SYNTHESIS OF THE C.10-C.18 SEGMENT OF FK-506
ASKIN, D
VOLANTE, RP
REAMER, RA
RYAN, KM
SHINKAI, I
[J]. TETRAHEDRON LETTERS, 1988, 29 (03) : 277 - 280
[2] CLAISEN REARRANGEMENTS OF LACTONIC (SILYL) ENOLATES - A NEW ROUTE OF FUNCTIONALIZED CYCLOALKENES
DANISHEFSKY, S
FUNK, RL
KERWIN, JF
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (22) : 6889 - 6891
[3] CATALYTIC ASYMMETRIC EPOXIDATION AND KINETIC RESOLUTION - MODIFIED PROCEDURES INCLUDING INSITU DERIVATIZATION
GAO, Y
HANSON, RM
KLUNDER, JM
KO, SY
MASAMUNE, H
SHARPLESS, KB
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (19) : 5765 - 5780
[4] CYCLOPHILIN - A SPECIFIC CYTOSOLIC BINDING-PROTEIN FOR CYCLOSPORIN-A
HANDSCHUMACHER, RE
HARDING, MW
RICE, J
DRUGGE, RJ
[J]. SCIENCE, 1984, 226 (4674) : 544 - 547
[5] CLAISEN REARRANGEMENT OF ALLYL ESTERS
IRELAND, RE
MUELLER, RH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1972, 94 (16) : 5897 - &
[6] FK-506, A NOVEL IMMUNOSUPPRESSANT ISOLATED FROM A STREPTOMYCES .2. IMMUNOSUPPRESSIVE EFFECT OF FK-506 INVITRO
KINO, T
HATANAKA, H
MIYATA, S
INAMURA, N
NISHIYAMA, M
YAJIMA, T
GOTO, T
OKUHARA, M
KOHSAKA, M
AOKI, H
OCHIAI, T
[J]. JOURNAL OF ANTIBIOTICS, 1987, 40 (09) : 1256 - 1265
[7] FK-506, A NOVEL IMMUNOSUPPRESSANT ISOLATED FROM A STREPTOMYCES .1. FERMENTATION, ISOLATION, AND PHYSICOCHEMICAL AND BIOLOGICAL CHARACTERISTICS
KINO, T
HATANAKA, H
HASHIMOTO, M
NISHIYAMA, M
GOTO, T
OKUHARA, M
KOHSAKA, M
AOKI, H
IMANAKA, H
[J]. JOURNAL OF ANTIBIOTICS, 1987, 40 (09) : 1249 - 1255
[8] DIASTEROSPECIFIC, NON-RACEMIC SYNTHESIS OF THE C.20-C.34 SEGMENT OF THE NOVEL IMMUNOSUPPRESSANT FK-506
MILLS, S
DESMOND, R
REAMER, RA
VOLANTE, RP
SHINKAI, I
[J]. TETRAHEDRON LETTERS, 1988, 29 (03) : 281 - 284
[9] STUDIES OF THE EFFECTS OF FK506 ON RENAL ALLOGRAFTING IN THE BEAGLE DOG
OCHIAI, T
NAGATA, M
NAKAJIMA, K
SUZUKI, T
SAKAMOTO, K
ENOMOTO, K
GUNJI, Y
UEMATSU, T
GOTO, T
HORI, S
KENMOCHI, T
NAKAGOURI, T
ASANO, T
ISONO, K
HAMAGUCHI, K
TSUCHIDA, H
NAKAHARA, K
INAMURA, N
GOTO, T
[J]. TRANSPLANTATION, 1987, 44 (06) : 729 - 733
[10] STUDIES OF THE INDUCTION AND MAINTENANCE OF LONG-TERM GRAFT ACCEPTANCE BY TREATMENT WITH FK506 IN HETEROTOPIC CARDIAC ALLOTRANSPLANTATION IN RATS
OCHIAI, T
NAKAJIMA, K
NAGATA, M
HORI, S
ASANO, T
ISONO, K
[J]. TRANSPLANTATION, 1987, 44 (06) : 734 - 738