HORMONAL EFFECTS OF AN ORALLY ACTIVE 4-AZASTEROID INHIBITOR OF 5-ALPHA-REDUCTASE IN HUMANS

被引：96

作者：

VERMEULEN, A

GIAGULLI, VA

DESCHEPPER, P

BUNTINX, A

STONER, E

机构：

[1] CATHOLIC UNIV LEUVEN,DEPT PHARMACOL,B-3000 LOUVAIN,BELGIUM

[2] MERCK SHARP & DOHME RES LABS,RAHWAY,NJ 07065

来源：

PROSTATE | 1989年 / 14卷 / 01期

关键词：

D O I：

10.1002/pros.2990140106

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：45 / 53

页数：9

共 19 条

[1]

BRUCHOVSKY N, 1968, J BIOL CHEM, V243, P2012

[2] PLASMA 5-ALPHA-ANDROSTANE-3-ALPHA, 17-BETA-DIOL AND URINARY 5-ALPHA-ANDROSTANE-3-ALPHA, 17-BETA-DIOL GLUCURONIDE, PARAMETERS OF PERIPHERAL ANDROGEN ACTION - A COMPARATIVE-STUDY [J].

DESLYPERE, JP ;

SAYED, A ;

PUNJABI, U ;

VERDONCK, L ;

VERMEULEN, A .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1982, 54 (02) :386-391

[3] STEROID 5ALPHA-REDUCTASE DEFICIENCY IN MAN - INHERITED FORM OF MALE PSEUDOHERMAPHRODITISM [J].

IMPERATO.J ;

GUERRERO, L ;

GAUTIER, T ;

PETERSON, RE .

SCIENCE, 1974, 186 (4170) :1213-1215

[4] SPLANCHNIC EXTRACTION AND CONVERSION OF TESTOSTERONE AND DIHYDROTESTOSTERONE IN MAN [J].

ISHIMARU, T ;

EDMISTON, WA ;

PAGES, L ;

HORTON, R .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1978, 46 (04) :528-533

[5]

KATO R, 1970, ENDOCRINOL JAPON, V17, P215

[6] ANDROGEN PRODUCTION AND SKIN METABOLISM IN HIRSUTISM [J].

KUTTENN, F ;

MOWSZOWICZ, I ;

SCHAISON, G ;

MAUVAISJARVIS, P .

JOURNAL OF ENDOCRINOLOGY, 1977, 75 (01) :83-91

[7] TESTOSTERONE 5-ALPHA-REDUCTION IN SKIN OF NORMAL SUBJECTS AND OF PATIENTS WITH ABNORMAL SEX DEVELOPMENT [J].

KUTTENN, F ;

MAUVAISJARVIS, P .

ACTA ENDOCRINOLOGICA, 1975, 79 (01) :164-176

[8] SPECIES-DIFFERENCES IN PROSTATIC STEROID 5-ALPHA-REDUCTASES OF RAT, DOG, AND HUMAN [J].

LIANG, T ;

CASCIERI, MA ;

CHEUNG, AH ;

REYNOLDS, GF ;

RASMUSSON, GH .

ENDOCRINOLOGY, 1985, 117 (02) :571-579

[9] INHIBITION OF TESTOSTERONE CONVERSION TO DIHYDROTESTOSTERONE IN MEN TREATED PERCUTANEOUSLY BY PROGESTERONE [J].

MAUVAISJ.P ;

KUTTENN, F ;

BAUDOT, N .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1974, 38 (01) :142-147

[10]

MAUVAISJARVIS P, 1976, ENDOCRINE FUNCTION H, P481

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