DETERMINATION OF PENTACHLOROPHENOL IN URINE - IMPORTANCE OF HYDROLYSIS

被引：34

作者：

EDGERTON, TR

MOSEMAN, RF

机构：

[1] Environmental Toxicology Division, Health Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1979年 / 27卷 / 01期

关键词：

D O I：

10.1021/jf60221a001

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

A gas chromatographic method for more reliable determination of pentachlorophenol (PCP) in urine has been developed. After hydrolysis and extraction the sample was reacted with diazomethane to produce the methyl ether of PCP prior to analysis by electron-capture gas chromatography. An acid alumina column clean-up system was developed to remove interferences from the sample extracts and allow detectability of 1 ppb PCP. Average recoveries of greater than 90% were obtained from urine fortified with known amounts of PCP. The importance of hydrolysis and comparisons of present methodologies will also be presented. © 1979, American Chemical Society. All rights reserved.

引用

页码：197 / 199

页数：3

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