DOES REVERSED-TYPE ANAPHYLAXIS IN HEALTHY-SUBJECTS MIMIC A REAL ALLERGIC REACTION

被引：15

作者：

HENOCQ, E ^{[1
]}

RIHOUX, JP ^{[1
]}

机构：

[1] UNION CHIM BELGE,BRAINE ALLEUD,BELGIUM

来源：

CLINICAL AND EXPERIMENTAL ALLERGY | 1990年 / 20卷 / 03期

关键词：

D O I：

10.1111/j.1365-2222.1990.tb02682.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Immediate and late cutaneous reactions were induced in healthy and atopic subjects by anti‐IgE challenge and a skin‐window technique was used in order to verify if the pattern of cells observed at 24 hr was similar in both groups. The study was first performed under basal conditions, and in a second double‐blind cross‐over step, it was performed again during treatment with cetirizine 10 mg b.i.d. and terfenadine 60 mg b.i.d. Anti‐IgE challenge was followed by a significant eosinophil accumulation in atopic subjects only. Cetirizine significantly inhibited this phenomenon while terfenadine showed a mild nonsignificant inhibitory effect. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：269 / 272

页数：4

共 27 条

[1]

ASSEM E S K, 1971, Clinical Allergy, V1, P353, DOI 10.1111/j.1365-2222.1971.tb00786.x

[2] CUTANEOUS EOSINOPHIL ACCUMULATION IN ATOPIC AND NON-ATOPIC INDIVIDUALS - EFFECT OF AN ECF-A TETRAPEPTIDE AND HISTAMINE [J].