MEIOTIC MATURATION IN XENOPUS-LAEVIS OOCYTES INITIATED BY INSULIN

被引：120

作者：

ELETR, M ^{[1
]}

SCHORDERETSLATKINE, S ^{[1
]}

BAULIEU, EE ^{[1
]}

机构：

[1] UNIV GENEVA,DEPT OBSTET & GYNECOL,CH-1211 GENEVA 4,SWITZERLAND

来源：

SCIENCE | 1979年 / 205卷 / 4413期

关键词：

D O I：

10.1126/science.472755

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Insulin can induce meiotic division in Xenopus laevis oocytes. This effect shows the specificity expected of a receptor-mediated mechanism. It is potentiated by ethynylestradiol, a steroid antagonist of progesterone (the natural hormone that provokes meiosis). The Xenopus laevis oocytes may serve as a model for the study of the poorly understood effect of insulin on cell division.

引用

页码：1397 / 1399

页数：3

共 26 条

[1] STEROID-INDUCED MEIOTIC DIVISION IN XENOPUS-LAEVIS OOCYTES - SURFACE AND CALCIUM [J].

BAULIEU, EE ;

GODEAU, F ;

SCHORDERET, M ;

SCHORDERETSLATKINE, S .

NATURE, 1978, 275 (5681) :593-598

[2] PREPARATION OF N-ALPHA-A1,N-EPSILON-B-29-ADIPOYLINSULIN, AN INTRAMOLECULARLY CROSSLINKED DERIVATIVE OF BEEF INSULIN [J].

BRANDENBURG, D .

HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1972, 353 (06) :869-+

[3]

BRANDENBURG D, 1974, DIABETOLOGIA, V10, P105

[4]

CLAUSEN T, 1974, ACTA ENDOCRINOL-COP, V77, P137

[5]

CLAUSEN T, 1974, ACTA ENDOCRINOL S, V77, P191

[6]

CUATRECASAS P, 1975, RECENT PROG HORM RES, V31, P37

[7] MOLECULAR-BASIS OF INSULIN ACTION [J].

CZECH, MP .

ANNUAL REVIEW OF BIOCHEMISTRY, 1977, 46 :359-384

[8] INTERACTIONS OF PROINSULIN WITH INSULIN RECEPTORS ON PLASMA-MEMBRANE OF LIVER [J].

FREYCHET, P .

JOURNAL OF CLINICAL INVESTIGATION, 1974, 54 (05) :1020-1031

[9] RECEPTOR-BINDING ASSAY OF CHEMICALLY MODIFIED INSULINS - COMPARISON WITH IN-VITRO AND IN-VIVO BIOASSAYS [J].

FREYCHET, P ;

BRANDENBURG, D ;

WOLLMER, A .

DIABETOLOGIA, 1974, 10 (01) :1-5

[10]

GODEAU F, 1978, CR ACAD SCI D NAT, V286, P685

← 1 2 3 →