DOPA REACTION TEST IN HAIR BULBS OF FETUSES AND ITS APPLICATION TO THE PRENATAL-DIAGNOSIS OF ALBINISM

被引：12

作者：

GERSHONIBARUCH, R

BENDERLY, A

BRANDES, JM

GILHAR, A

机构：

[1] RAPPOPORT INST MED RES,HAIFA,ISRAEL

[2] RAMBAM MED CTR,DEPT OBSTET & GYNECOL,IL-31096 HAIFA,ISRAEL

[3] TECHNION ISRAEL INST TECHNOL,FAC MED,SKIN RES LAB,HAIFA,ISRAEL

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 1991年 / 24卷 / 02期

关键词：

D O I：

10.1016/0190-9622(91)70030-6

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

No information is available on the amount of tyrosinase normally present in fetuses. A dopa reaction test in hair bulbs from the scalp of normal fetuses obtained after abortion showed that tyrosinase is present in fetuses as early as 17 weeks. Only faint activity was detected in skin specimens other than from the scalp. This assay can serve as a quick and reliable method for the prenatal diagnosis of tyrosinase-negative albinism.

引用

页码：220 / 222

页数：3

共 10 条

[1] PRENATAL-DIAGNOSIS OF OCULOCUTANEOUS ALBINISM BY ELECTRON-MICROSCOPY OF FETAL SKIN [J].